Histamine iontophoresis on the viability of random skin flap in rats

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چکیده

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Histamine iontophoresis on the viability of random skin flap in rats.

PURPOSE To evaluate the effects of the histamine iontophoresis on the random skin flap viability in rats. METHODS Sixty adult male Wistar rats were used. A cranially-based dorsal skin flap measuring 10 x 4 cm was raised and a plastic barrier was placed between the flap and its bed. After the surgical procedure, the animals were randomized into four groups (G1-G4) (n=15 each group) as follows:...

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Favorable effects of progesterone on skin random flap survival in rats

Objective(s): The aim of this study is to determine the effects of progesterone treatment on the survival of random skin flaps. Materials and Methods: McFarlane flaps were established and 40 male rats were randomly assigned to the progesterone-treated as the test group or normal saline-treated as the control group. Progesterone or normal saline (10 mg/kg) was administered intraperitoneally onc...

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Adipose-derived stem cells (ADSC) in the viability of random skin flap in rats.

PURPOSE To evaluate the effects of the adipose-derived stem cells (ADSC) in the viability of random skin flap in rats. METHODS Thirty five adult male Wistar rats (weight 250-300 g) were used. ADSC were isolated from adult male rats (n=5). ADSC were separated, cultured and then analyzed. A dorsal skin flap measuring 10 x 4 cm was raised and a plastic barrier was placed between the flap and its...

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The Effect of Enoxaparin and Clopidogrel on Survival of Random Skin Flap in Rat Animal Model

BACKGROUND Necrosis of skin flaps is considered as an important complication in reconstructive surgery. We conducted an experimental study to investigate the efficacy of low-molecular weight heparin, clopidogrel and their combination to improve the flap survival. METHODS Forty male, adult Sprague-Dawlay rats were divided randomly into 4 groups. Standard rectangular, distally based dorsal ran...

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ژورنال

عنوان ژورنال: Acta Cirurgica Brasileira

سال: 2009

ISSN: 0102-8650

DOI: 10.1590/s0102-86502009000100010